The Central Limit Theorem occasionally results in extremely slow convergence to the Normal distribution, making the corresponding approximation virtually useless (a typical example being the sample ...
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There is an issue linked to the use the Truncated wrapper on the normal function and how it is handled by JAX (cf example below). So this fails when trying to sample with blackjax or numpyro. On the ...
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The normal distribution is a concept in statistics that assumes all values are distributed in the same pattern. It requires symmetry and consistent proportions in the distribution of values. Normal ...
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Would it be possible to add the Normal sample GT/DP/AO to the somatic vcf just for comparison -- for example you can imagine that you have a few "alt reads" in the normal sample compared to 5% or 10% ...