Randomized controlled trials (RCTs) are considered the gold standard for evaluating surgical interventions for benign prostatic hyperplasia (BPH). However, the validity and reliability of their ...

Copyright: © 2025 The Author(s). Published by Elsevier Ltd. Individual prediction uncertainty is a key aspect of clinical prediction model performance; however ...

Join the ORBIT (Observational Research Building Interdisciplinary Therapeutic Advances) Interdisciplinary Hub for the upcoming seminar, "Sample Size and Power Calculations in Causal Inference with ...

Equivalence tests often are used for demonstrating bioequivalence between two biopharmaceutical formulations, with the two one-sided test (TOST) being a common, regulator-accepted statistical method ...

For all 4 algorithms, more balanced classes (multiplier: 0.93-0.96 for a 1% increase in minority class proportion) were associated with decreased sample size. Other characteristics varied in ...

Accurate sample size estimation is a cornerstone of successful Institutional Review Board (IRB) proposals, as it establishes the feasibility of clinical studies and ensures they are sufficiently ...

We read the study conducted by Drews et al 1 with great interest. In this prospective randomised controlled trial of patients undergoing hot-snare EMR of flat lesions in the duodenum (≥10 mm) and ...

Objective Large-scale mortality trials require reliable secondary assessments of impairment. We compared the Ages and Stages Questionnaire (ASQ-3), a screening tool self-administered by parents, in ...

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