Medwin Clinicians Did You Know!!! Medicine: Beyond the Basics. Treatment for Syphillis Your partner just told you they tested positive for syphilis, and now you’re wondering what happens next. Let’s break down the testing process because knowledge is power. First, there are two main types of tests. Screening tests look for antibodies your body makes in response to the infection. These include the RPR and VDRL tests. If that comes back positive, your doctor will confirm it with a more specific te