Mushies on Instagram: "Psilocybin appears to weaken cortico-cortical feedback loops (the circuits that keep signals bouncing endlessly around the cortex) while strengthening pathways that route sensory information toward subcortical regions that turn perception into action. Alex Kwan says: “Rumination is one of the main features of depression, where people keep dwelling on the same negative thoughts. By reducing some of these feedback loops, our findings are consistent with the idea that psilocy