Scientists have found evidence that DMT (N,N-Dimethyltryptamine)—a compound naturally produced in small amounts by the human body—may play a role in protecting and repairing brain tissue after injury. What Researchers Observed: • In laboratory and animal studies, DMT helped stabilize the blood-brain barrier after stroke-like damage • It significantly reduced brain inflammation, a major cause of secondary injury after strokes • DMT appears to activate sigma-1 receptors, which are linked to cell s